Tag Archives: Flu

How Pandemics Changed History

How will the COVID-19 pandemic end? Will it change the world? Will some countries emerge stronger, while others appear weak due to their inability to handle the virus? Will the pandemic force long-term impacts on economies and cultures?

Wars carve our history. They lead to the downfall of some civilizations and the rise of others. Pandemics have also changed history, and pandemics and wars often coincide. Disease can weaken a strong civilization, allowing its lesser foe to prevail in battle. Also, many times over the millennia, marauding warriors have returned home from war bringing with them a terrible disease. Sometimes, an infectious disease gains a foothold during battle, and soldiers confined together in close quarters provide the perfect breeding ground for the virus to spread.

Around 430 B.C., Athens and Sparta went to war, and soon after, a strange disease developed in Athens. According to the Greek historian Thucydides, people in good health suddenly became ill with red and inflamed eyes and a bloody throat and tongue. Experts do not know what caused this epidemic, but they have suggested everything from typhoid fever to Ebola. As the deadly infection spread, the war raged. As many as 100,000 people died from the disease, and Athens finally surrendered to Sparta.

In A.D. 165-180, Roman soldiers returned from a campaign, carrying home a pandemic, known as the Antonine Plague. The disease, which might have been smallpox, killed over 5 million people. The epidemic caused instability and war throughout the Roman Empire, leading to the beginning of its downfall.

The Plague of Justinian from A.D. 541-542 was the bubonic plague, and it ravaged Constantinople before spreading to Europe, Asia, North Africa, and Arabia. This plague marked the beginning of the decline of the Byzantine Empire.

The bubonic plague also caused the Black Death from 1346-1353. This devastating pandemic wiped out over half of Europe’s population, but it also changed the course of Europe’s history in a positive way. Large numbers of laborers died from the plague, and those who remained demanded higher wages. The surviving laborers had access to better food, and the loss of cheap labor led to technological innovation.

In the 16th century, European explores brought smallpox and other Eurasian diseases to the Americas, wiping out as many as 90% of the indigenous people in the Western Hemisphere and causing the collapse of the Inca and Aztec civilizations. After disease weakened the Incas and Aztecs, the Europeans easily conquered them.

While the previous examples stem from far back in our history, the 1918-1919 flu presents a more recent case. This pandemic began during WWI. Experts disagree about where the flu originated, but most agree the lethal virus spread quickly due to the cramped conditions of soldiers in barracks and the poor nutrition during the war. President Woodrow Wilson was so intent on boosting morale and keeping the country focused on patriotism and winning the war that he refused to talk about the deadly influenza virus spreading like wildfire among the troops. By the end of WWI, more soldiers died from the flu than on the battlefield. The 1918-1919 flu killed 675,000 Americans and between 50 and 100 million people worldwide.

In April 1919, just as the war ended, President Wilson caught the flu. When it was time to sign the peace treaty in Paris, an extremely ill and weakened Wilson caved to demands of the French for a punishing peace agreement with Germany. In return for conceding to the French on the tone and content of the treaty, the French agreed to Wilson’s wishes to form the League of Nations. Many historians believe the harsh treatment toward Germany at the end of WWI lead the country down the path to hyperinflation, chaos, nationalism, militarization, the rise of Adolf Hitler, and WWII.

A major world event such as a pandemic is bound to leave lasting impacts. We can already predict some changes in our lives. Online virtual meetings, education, and doctor’s visits have become more frequent and likely will remain so, even once the pandemic ends. Will a move away from working at the office toward working at home decentralize our cities? Will our hypervigilance over avoiding infection continue once we have a vaccine for COVID-19, or will we again display indifference in the presence of pathogens? Will our economy recover, or will we suffer a damaging and possibly fatal blow from this virus? How will other countries fare?

Perhaps the final chapter on the COVID-19 virus will not be written for decades when scholars can look back from a distance and see the effect the virus had on our lives, our cultures, and our countries. Other pandemics have caused the fall of empires. Will this one cause significant harm in the long run?


Robin Barefield is the author of four Alaska wilderness mystery novels, Big Game, Murder Over Kodiak, and The Fisherman’s Daughter, and Karluk Bones. Also, sign up below to subscribe to her free, monthly newsletter on true murder and mystery in Alaska, and listen to her podcast, Murder and Mystery in the Last Frontier.


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Influenza: The Flu

While the flu is something we would rather avoid, most of us don’t fear the flu virus. But maybe we should. Influenza viruses are complex, containing strands of RNA twisted together. When the strands untwist to replicate, they break and sometimes recombine with fragments of other viruses, resulting in new viral forms. Virologists cannot predict these mutations. Flu viruses reside in a variety of host species, and the virus can pick up nasty tricks as it moves from animal to animal, recombining with other flu viruses before moving on to infect a host of another species. By the time the virus reaches man, it might be highly contagious, extremely lethal, and nothing humans have ever seen before. The novel virus could quickly race around the planet, leaving destruction in its wake.

For those infected with the influenza virus, symptoms range from mild to severe. The most common symptoms include high fever, runny nose, sore throat, muscle and joint pain, headache, coughing, and fatigue. The influenza virus occasionally causes severe illness, including primary viral pneumonia and secondary bacterial pneumonia.

Influenza Virus

Three types of influenza viruses affect humans. These are known as types A,B, and C. A fourth type (D) has not been known to affect humans, but virologists believe it could. Influenzavirus A is the most worrisome of the four types, because wild aquatic birds are the natural hosts for influenza A, and the virus sometimes jumps to other species, causing massive outbreaks of infection in domestic poultry and creating pandemics of influenza in humans. Recent human pandemics caused by the influenza A virus include the 1918/1919 flu, the 1957 Asian Flu, and the 2004 bird flu.

Most experts consider the 1918/1919 flu (Spanish flu) pandemic one of the most baffling and terrifying pandemics of all time. Approximately 250,000 to 500,000 people worldwide die from the flu each year. The 1918/1919 (Spanish) flu, though, killed an estimated 20-50 million humans over the course of a year. Some estimates range as high as 100 million deaths. More terrifying yet, though, was who the virus killed. The very old, very young, or those with underlying health conditions usually succumb to the common flu, but the Spanish flu killed young, otherwise healthy adults.

Experts today still argue over why the Spanish flu killed the young and healthy, but many believe the virus triggered a cytokine storm, which is an overreaction of the body’s immune system. This storm proved particularly deadly for young adults with robust immune systems.

Historians and virologists also argue over where the Spanish flu originated, but everyone agrees it did not come from Spain. Since Spain remained a neutral nation during WWI, it did not censor its press, and reporters freely documented early accounts of the disease, causing many people to think the flu originated in Spain. Some experts believe the 1918 flu pandemic began in Haskell County, Kansas, and quickly spread from there to Fort Riley when an enlisted man went home to Haskell for a few days, became infected, and returned to the army base. In the overcrowded barracks on base, the flu quickly spread.

The Spanish flu suddenly burned out in the Spring of 1919. While this H1N1 influenza A virus has not returned since, epidemiologist fear it will reappear. This pandemic occurred over one-hundred years ago, so few people alive now have immunity to this strain, and it could again exact a nasty toll.

Flu experts study the world and watch carefully for the next possible flu epidemic. Infectious disease experts say it is not a matter of if but when the next flu pandemic will occur.

Robin Barefield is the author of four Alaska wilderness mystery novels, Big Game, Murder Over Kodiak, and The Fisherman’s Daughter, and Karluk Bones. Also, sign up below to subscribe to her free, monthly newsletter on true murder and mystery in Alaska, and listen to her podcast, Murder and Mystery in the Last Frontier.

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Sign Up for my free, monthly Mystery Newsletter about true crime in Alaska.